Publications

2020

Reppucci CJ, Veenema AH. The social versus food preference test: A behavioral paradigm for studying competing motivated behaviors in rodentsMethodsX 7:101119.

Reppucci CJ, Brown LA, Chambers AQ, Veenema AH. Wistar rats and C57BL/6 mice differ in their motivation to seek social interaction versus food in the Social versus Food Preference Test. Physiol Behav 227:113162.

Reppucci CJ, Gergely CK, Bredewold R, Veenema AH. Involvement of orexin/hypocretin in the expression of social play behaviour in juvenile rats. International Journal of Play 9:108-127.

DiBenedictis BT, Cheung HK, Nussbaum ER, Veenema AH. Involvement of ventral pallidal vasopressin in the sex-specific regulation of sociosexual motivation in rats. Psychoneuroendocrinology 111:104462.

2019

Hodges TE, Eltahir AM, Patel S, Bredewold R, Veenema AH, McCormick CM. Effects of oxytocin receptor antagonism on social function and corticosterone release after adolescent social instability in male rats. Horm Behav 116:104579.

Worley NB, Dumais KM, Yuan JV, Newman LE, Alonso AG, Gillespie TC, Hobbs NJ, Breedlove SM, Jordan CL, Bredewold R, Veenema AH. Estrogen and androgen receptor activation contribute to the masculinization of oxytocin receptors in the bed nucleus of the stria terminalis of rats. J Neuroendocrinology Jun 24:e12760.

Smith CJW, DiBenedictis BT, Veenema AH. Comparing vasopressin and oxytocin fiber and receptor density patterns in the social behavior neural network: Implications for cross-system signaling. Front Neuroendocrinol. 53:100737.

2018

Bredewold R, Nascimento NF, Ro GS, Cieslewski SE, Reppucci CJ, Veenema AH. Involvement of dopamine, but not norepinephrine, in the sex-specific regulation of juvenile socially rewarding behavior by vasopressin. Neuropsychopharmacology 43:2109-2117.

Bredewold R, Veenema AH. Sex differences in the regulation of social and anxiety-related behaviors: insights from vasopressin and oxytocin brain systems. Curr Opin Neurobiol, 49:132-140.

Reppucci CJ, Gergely CK, Veenema AH. Activation patterns of vasopressinergic and oxytocinergic brain regions following social play exposure in juvenile male and female rats. J Neuroendocrinol, 30:e12582.

Smith CJW, Ratnaseelan AM, Veenema AH. Robust age, but limited sex, differences in mu-opioid receptors in the rat brain: relevance for reward and drug-seeking behaviors in juvenilesBrain Struct Funct, 223:475-488.

Smith CJW, Wilkins KB, Li S, Tulimieri MT, Veenema AH. Nucleus accumbens mu opioid receptors regulate context-specific social preferences in the juvenile ratPsychoneuroendocrinology, 89:59-68.

2017

Raam T, McAvoy KM, Besnard A, Veenema AH, Sahay A. Hippocampal oxytocin receptors are necessary for discrimination of social stimuli. Nat Commun, Dec 8;8(1):2001.

Hodges TE, Baumbach JL, Marcolin ML, Bredewold R, Veenema AH, McCormick CM. Social instability stress in adolescent male rats reduces social interaction and social recognition performance and increases oxytocin receptor binding. Neuroscience, 359:172-182.

Smith CJW, Mogavero JN, Tulimieri MT, Veenema AH. Involvement of the oxytocin system in the nucleus accumbens in the regulation of juvenile social novelty-seeking behavior. Horm Behav, 93:94-98.

Dumais KM, Kulkarni PP, Ferris CF, Veenema AH. Sex differences in neural activation following different routes of oxytocin administration in awake adult rats. Psychoneuroendocrinology, 81: 52-62.

DiBenedictis BT, Nussbaum ER, Cheung HK, Veenema AH (2017) Quantitative mapping reveals age and sex differences in vasopressin, but not oxytocin, immunoreactivity in the rat social behavior neural network. J Comp Neurol, 525:2549-2570.

Varian BJ, Poutahidis T, DiBenedictis BT, Levkovich T, Ibrahim Y, Didyk E, Shikhman L, Cheung HK, Hardas A, Ricciardi CE, Kolandaivelu K, Veenema AH, Alm EJ, Erdman SE. Microbial lysate upregulates host oxytocin. Brain Behav Immun, 61:36-49.

Smith CJ, Poehlmann ML, Li S, Ratnaseelan AM, Bredewold R, Veenema AH. Age and sex differences in oxytocin and vasopressin V1a receptor binding densities in the rat brain: focus on the social decision-making network. Brain Struct Funct, 222:981-1006.

2016

Dumais KM, Alonso AG, Bredewold R, Veenema AH. Role of the oxytocin system in amygdala subregions in the regulation of social interest in male and female rats. Neuroscience, 330:138-149.

Dumais KM, Alonso AG, Immormino MA, Bredewold R, Veenema AH. Involvement of the oxytocin system in the bed nucleus of the stria terminalis in the sex-specific regulation of social recognition. Psychoneuroendocrinology, 64:79-88.

Dumais KM, Veenema AH. Vasopressin and oxytocin receptor systems in the brain: sex differences and implications for social behavior. Frontiers in Neuroendocrinology, 40:1-23.

Dumais KM, Veenema AH. Presence and absence of sex differences in structure and function of the brain oxytocin system: Implications for understanding social behavior. In: Sex Differences in the Central Nervous System, Elsevier, R. Shansky & J. Johnson (Eds), p. 247-284.

2015

Bredewold R, Schiavo JK, Van der Hart M, Verreij M, Veenema AH. Dynamic changes in extracellular release of GABA and glutamate in the lateral septum during social play behavior in juvenile rats: Implications for sex-specific regulation of social play behavior. Neurosci, 307:117-27.

Ferris CF, Yee J, Kenkel W, Dumais KM, Moore K, Veenema AH, Kulkarni P, Perkeybile AM, Carter CS. Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats. Front Behav Neurosci, Sep 17;9:245.

Smith CJ, Wilkins KB, Mogavero JN, Veenema AH. Social novelty investigation in the juvenile rat: modulation by the mu-opioid system. J Neuroendocrinol 27(10):752-764.

2014

Bredewold R, Smith CJW, Dumais KM, Veenema AH. Sex-specific modulation of juvenile social play behavior by vasopressin and oxytocin depends on social context. Front Behav Neurosci doi: 10.3389/fnbeh.2014.00216.

2013

Dumais KM, Bredewold R, Mayer TE, Veenema AH. Sex differences in oxytocin receptor binding in forebrain regions: correlations with social interest in brain region- and sex-specific ways. Hormones & Behavior, 64:693-701.

Veenema AH, Bredewold R, De Vries GJ. Sex-specific modulation of juvenile social play by vasopressin. Psychoneuroendocrinology, 38:2554-61.

Lukas M, Toth I, Veenema AH, Neumann ID. Oxytocin mediates rodent social memory within the lateral septum and the medial amygdala depending on the relevance of the social stimulus: Male juvenile versus female adult conspecifics.Psychoneuroendocrinology, 38:916-26.

2012

Beiderbeck DI, Reber SO, Havasi A, Bredewold R, Veenema AH, Neumann ID. High and abnormal forms of aggression in rats with extremes in trait anxiety – Involvement of the dopamine system in the nucleus accumbens. Psychoneuroendocrinology, 37:1969-80.

Taylor PV, Veenema AH, Paul MJ, Bredewold R, Isaacs S, de Vries GJ. Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats. Biology of Sex Differences, Jun 14;3(1):15.

de Vries GJ, Veenema AH, Brown CH. Vasopressin and oxytocin: keys to understanding the neural control of physiology and behaviour. J Neuroendocrinol, 24:527.

Veenema AH. Toward understanding how early-life social experiences alter oxytocin- and vasopressin-regulated social behaviors. Hormones & Behavior, 61:304-12.

Veenema AH, Bredewold R, De Vries GJ. Vasopressin regulates social recognition in juvenile and adult rats of both sexes, but in sex- and age-specific ways. Hormones & Behavior, 61:50-6.

2011

Lukas M, Toth I, Reber SO, Slattery DA, Veenema AH, Neumann ID. The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice. Neuropsychopharmacology, 36:2159-68.

Lukas M, Bredewold R, Landgraf R, Neumann ID, Veenema AH. Early life stress impairs social recognition due to a blunted response of vasopressin release within the septum of adult male rats. Psychoneuroendocrinology, 36:843-853.

2010

Neumann ID, Veenema AH, Beiderbeck DI. Aggression and anxiety: social context and neurobiological links. Front Behav Neurosci, Mar 30;4:12.

Veenema AH, Beiderbeck DI, Lukas M, Neumann ID. Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression. Horm Behav, 58:273-281.

Lukas M, Bredewold R, Neumann ID, Veenema AH. Maternal separation interferes with the development of vasopressin and oxytocin receptors in the brain. Neuropharmacology, 58:78-87.

2009

Veenema AH. Early life stress, the development of aggression and neurobiological correlates: What can we learn from animal models? Front Neuroendocrinol, 30:497–518.

Veenema AH, Neumann ID. Maternal separation enhances offensive play-fighting in juvenile male rats. Psychoneuroendocrinology, 23:463-467.

2008

Veenema AH, Neumann ID. Role of central vasopressin and oxytocin release in social behaviours. Prog Brain Res, 170:261-276.

Veenema AH, Reber SO, Selch S, Obermeier F, Neumann ID. Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice. Endocrinology, 149:2727-2736.

Reber SO, Obermeier F, Straub HR, Veenema AH, Neumann ID. Chronic psychosocial stress (subordinate colony housing) increases the severity of a DSS-induced colitis in mice – implications and mechanisms. Stress, 11:225-234.

2007

Beiderbeck DI, Neumann ID, Veenema AH. Differences in intermale aggression are accompanied by opposite vasopressin release patterns within the septum in rats bred for high and low anxiety. Eur J Neurosci, 26:3597-3605.

Veenema AH, Neumann ID. Neurobiological mechanisms of aggression and stress coping: a comparative study in mouse and rat selection lines. Brain Behav Evol, 70:274-285.

Veenema AH, de Kloet ER, de Wilde MC, Roelofs AJ, Kawata M, Buwalda B, Neumann ID, Koolhaas JM, Lucassen PJ. Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice. J Neuroendocrinol, 19:489-498.

Veenema AH, Bredewold R, Neumann ID. Opposite effects of maternal separation on intermale and maternal aggression in C57Bl/6 mice: link to hypothalamic vasopressin and oxytocin immunoreactivity. Psychoneuroendocrinology, 32:437-50.

Reber SO, Birkeneder L, Veenema AH, Obermeier F, Falk W, Straub RH, Neumann ID. Adrenal insufficiency and colonic inflammation following a novel chronic psycho-social stress paradigm in mice: implications and mechanisms. Endocrinology, 148:670-82.

Veenema AH, Torner L, Blume A, Beiderbeck DI, Neumann ID. Low inborn anxiety correlates with high intermale aggression: Link to ACTH response and neuronal activation of the hypothalamic paraventricular nucleus. Horm Behav, 51:11-19.

2006

Veenema AH, Blume A, Niederle D, Buwalda B, Neumann ID. Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin. Eur J Neurosci, 24:1711-20.

Feldker DE, Morsink MC, Veenema AH, Datson NA, Proutski V, Lathouwers D, de Kloet ER, Vreugdenhil E. The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates. Brain Res, 1089:10-20.

Neumann ID, Torner L, Toschi N, Veenema AH. Oxytocin actions within the supraoptic and paraventricular nuclei: differential effects on peripheral and intranuclear vasopressin release. Am J Physiol Regul Integr Comp Physiol, 291:R29-36.

2005

Veenema AH, Sijtsma B, Koolhaas JM, De Kloet ER. The stress response to sensory contact in mice: genotype effect of the stimulus animal. Psychoneuroendocrinology, 30:550-557.

Veenema AH, Cremers TIFH, Jongsma M, Steenbergen P, De Boer SF, De Kloet ER, Koolhaas JM. Differential effects of two 5-HT1a receptor agonists on forced swimming behaviour and 5-HT metabolism in low and high aggressive mice. Psychopharmacology, 178:151-160.

Buwalda B, Kole MHP, Veenema AH, Huininga M, De Boer SF, Korte SM, Koolhaas JM. Long-term effects of social stress on brain and behavior: a focus on hippocampal functioning. Neurosci Biobehav Rev, 29:83-97.

2004

Veenema AH, Koolhaas JM, De Kloet ER. Basal and stress-induced differences in HPA axis, 5-HT responsiveness and hippocampal cell proliferation in two mouse lines. Ann N Y Acad Sci, 1018: 255-265.

2003

Feldker DEM, Datson NA, Veenema AH, Proutski V, Lathouwers D, De Kloet ER, Vreugdenhil E. GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications. J Neuroscience Res, 74:701-716.

Sluyter F, Arseneault L, Moffitt TE, Veenema AH, de Boer SF, Koolhaas JM. Towards an animal model for antisocial behavior: parallels between mice and men. Behav Genet, 33:563-574.

Veenema AH, Meijer OC, De Kloet ER, Koolhaas JM. Genetic selection for coping style predicts stressor susceptibility. J Neuroendocrinol, 15:256-267.

Veenema AH, Meijer OC, De Kloet ER, Koolhaas JM, Bohus BG. Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression. Horm Behav, 43:197-204.

Feldker DE, Datson NA, Veenema AH, Meulmeester E, De Kloet ER, Vreugdenhil E. Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice. Eur J Neurosci, 17:379-387.

2002

Van Riel E, Meijer OC, Veenema AH, Joëls M. Hippocampal serotonin responses in short and long attack latency mice. J Neuroendocrinol, 14:234-239.

2000

Abraham I, Harkany T, Horvath KM, Veenema AH, Penke B, Nyakas C, Luiten PG. Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis. J Neuroendocrinol, 12:486-94.

1997

Abraham I, Veenema AH, Nyakas C, Harkany T, Bohus BG, Luiten PG. Effect of corticosterone and adrenalectomy on NMDA-induced cholinergic cell death in rat magnocellular nucleus basalis. J Neuroendocrinol, 9:713-720.